Garyfallos Konstantinoudis

Discussion In this nationwide study in England investigating the short-term effect of ambient summer temperature on asthma hospitalisations during 2002–2019, we find evidence of an increased risk of asthma hospitalisation associated with increasing temperature. The effect of ambient temperature exposure appears to be modified by sex and age, with males aged between 16 and 64 years being the most vulnerable population.

Discussion This is the first nationwide case-crossover study in England investigating the short-term effects of heat exposure on COPD hospitalisation. After accounting for confounding, the results indicate that for every 1°C increase in heat exposure the COPD hospitalisation risk increases by 1.47% (95% CrI 1.19% to 1.73%), with evidence that PM2.5 and O3 mediate this relationship. We found weak evidence of an effect modification by sex and age.

Ambient heat exposure and COPD hospitalisations in England: a nationwide case-crossover study during 2007–2018 http://orcid.org/0000-0001-7493-9334Garyfallos Konstantinoudis1, http://orcid.org/0000-0001-9166-3958Cosetta Minelli2, Ana Maria Vicedo-Cabrera3,4, Joan Ballester5, Antonio Gasparrini6,7,8, Marta Blangiardo1 1MRC Centre for Environment and Health, Imperial College London, London, UK 2NHLI, Imperial College London National Heart and Lung Institute, London, UK 3Institute of Social and...