Gayatri Rao

The day after CBER’s Cellular, Tissue, and Gene Therapies Advisory Committee meeting on Capricor Inc.’s Deramiocel for the treatment of cardiomyopathy in DMD, the Advisory Committee met on July 30, 2026, to discuss Replimune’s BLA resubmission seeking accelerated approval of RP1 (vusolimogene oderparepvec) in combination with nivolumab for advanced melanoma after progression on anti-PD-1 therapy. Replimune submitted a BLA on November 22, 2024, based on a single-arm Phase 2 IGNYTE study.

After more than a year with nary an adcomm (just 2 drug approval-related meetings in the Makary era), CBER’s Cellular, Tissue, and Gene Therapies Advisory Committee meetings came back with a vengeance last week with back-to-back meetings to discuss two seemingly controversial cell and gene therapies that received complete response letters (CRLs) and are now under review following BLA resubmissions: Capricor’s Deramiocel for DMD and Replimune’s RP1 for advanced melanoma.

Today’s fourth post is the analysis of the song, Pasand aa gayi, from the movie, Mehboobki Mehendi (1971). The song has been analysed based on its context and visualization. The song, Pasand aa gayi, was featured in Rahul Theaters (India) produced Muslim social, Mehboobki Mehendi (1971), produced and directed by H S Rawail. The movie starred Rajesh Khanna, Leena Chandavarkar, Pradeep Kumar, etc. The movie begins with Shabana (Leena Chandavarkar) performing at a college function.