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Gazanfer Belge

As seen in: Nature, MDPI
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Articles

MicroRNA-371a-3p-The Novel Serum Biomarker in Testicular Germ Cell Tumors

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By Tim Nestler, Gazanfer Belge, Klaus-Peter Dieckmann, Justine Schoch
| MDPI
Abstract : Simple Summary This review describes that miR371 is much more sensitive and specific than the classical serum biomarkers of testicular germ cell cancer. There is a huge potential for miR371 for initial diagnosis, monitoring treatment, and follow-up. However, miR371 is not expressed in teratoma. Currently, studies are underway to determine the importance of miR371 in the early detection of recurrences of testicular tumors under surveillance.
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Application of miRNAs in the diagnosis and monitoring of testicular germ cell tumours

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By Kristian Almstrup, João Lobo, Nina Mørup, Gazanfer Belge
| Nature Verified
Abstract Testicular germ cell tumours (TGCTs) are the most frequent cancer type in young men and originate from the common precursor germ cell neoplasia in situ (GCNIS). For decades, clinical management of patients with TGCT has relied on classic serum tumour markers: α-fetoprotein, human chorionic gonadotropin subunit-β and lactate dehydrogenase.
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