Geertruida Slinger

New-onset seizure-like events are common, particularly in children, but differentiating epilepsy from its mimics is challenging. First seizure clinics may improve and accelerate diagnosis. In our cohort, 68.6% received their diagnosis at first consultation, and less than 3% were misdiagnosed. This study can serve as a reference framework for the distribution and specification of diagnoses in children with new-onset seizure-like events.

Objective Guidelines suggest considering antiseizure medication (ASM) discontinuation in seizure-free patients with epilepsy. Past work has poorly explored how discontinuation effects vary between patients. We evaluated 1) What factors modify the influence of discontinuation on seizure risk; and 2) The range of seizure risk increase due to discontinuation across low- versus high-risk patients.