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As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Articles
Connexin‐36‐positive gap junctions in ventral tegmental area GABA neurons sustain opiate dependence
AAV adeno-associated virus ANOVA analysis of variance AP anterior–posterior BDNF brain-derived neurotrophic factor CFP cyan fluorescent protein CFPER cyan fluorescent protein excision reporter CPA conditioned place aversion CPP conditioned place preference CTB cholera toxin b subunit CTCF corrected total cell fluorescence Cx36 connexin-36 DV dorso-ventral KO knockout NAc nucleus accumbens ODW opiate-dependent and withdrawn pCREB phosphorylated cAMP response element-binding protein TPP...
Administration of brain‐derived neurotrophic factor in the ventral tegmental area produces a switch from a nicotine nondependent D1R‐mediated motivational state to a nicotine dependent‐like D2R‐mediated motivational state
RESEARCH REPORT Taryn E. Grieder, Taryn E.
Deletion of α5 nicotine receptor subunits abolishes nicotinic aversive motivational effects in a manner that phenocopies dopamine receptor antagonism
Nicotine addiction is a worldwide epidemic that claims millions of lives each year. Genetic deletion of ?5 nicotinic acetylcholine receptor (nAChR) subunits has been associated with increased nicotine intake, however, it remains unclear whether acute nicotine is less aversive or more rewarding, and whether mice lacking the ?5 nAChR subunit can experience withdrawal from chronic nicotine.
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