George Hany Eskander

References 1  Low ZX, Yeo KA, Sharma VK, Leung GK, McIntyre RS, Guerrero A, Lu B, Sin Fai Lam CC, et al. Prevalence of Burnout in Medical and Surgical Residents: A Meta-Analysis. Int J Environ Res Public Health 2019; 16(9): 1479. | Crossref | Google Scholar | PubMed | 2  Shanafelt TD, Hasan O, Dyrbye LN, Sinsky C, Satele D, Sloan J, West CP. Changes in Burnout and Satisfaction With Work-Life Balance in Physicians and the General US Working Population Between 2011 and 2014.

1. Introduction Clostridioides difficile, clinically known as Clostridium difficile, is an anaerobic, gram-positive, spore-forming, toxin-producing bacillus. C. difficile colonizes the large intestine and causes disease predominantly through its production of cytoskeletal-modifying exotoxins. These toxins mediate disease by triggering colonocyte death, causing the loss of intestinal barrier function, and provoking neutrophilic colitis [1]. C.