Georgia Charkoftaki on Muck Rack

Georgia Charkoftaki

New Haven, New York
As seen in: Nature
Assistant Professor of Spatial Redox Biology Columbian University @ColumbiaPS
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Articles

Glycosite mapping and in situ mass spectrometry imaging of MUC2 glycopeptides via on-slide mucinase digestion

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By Sarah C. Lowery, Mikaela K. Ribi, Joann Chongsaritsinsuk, Isabella Tran, Grace Grimsley, Rachel Stubler, Keira E. Mahoney, Taryn M. Lucas, Georgia Charkoftaki, Álvaro J. Santos-Neto, Nissi M. Varki, Vasilis S. Vasiliou, Michael Angelo, Richard Drake, Stacy A. Malaker
| Nature Verified
Abstract Current analytical techniques are limited in their ability to interrogate the mechanistic relationship between aberrant mucin glycosylation and malignancy. Herein, we describe a method for mapping specific mucin glycoforms in diseased tissue, enabling correlation of the tumor glycan profile with malignant features.
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A Guide to MALDI Imaging Mass Spectrometry for Tissues

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By Jessica Moore Verified, Georgia Charkoftaki
| dx.doi.org
Download Hi-Res ImageDownload to MS-PowerPointCite This:J. Proteome Res. 2023, XXXX, XXX Terms & Conditions Most electronic Supporting Information files are available without a subscription to ACS Web Editions. Such files may be downloaded by article for research use (if there is a public use license linked to the relevant article, that license may permit other uses).
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