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Gerard Llibre-Palomar on Muck Rack

Gerard Llibre-Palomar

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Articles

Epigenetically driven and early immune evasion in colorectal cancer evolution - Nature Genetics

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By Eszter Lakatos, Jacob Househam, Timon Heide, Nicholas Trahearn, Luis Cisneros, Inmaculada Spiteri, George D. Cresswell, Carlo C. Maley, Marnix Jansen, Manuel Rodriguez-Justo, Ann-Marie Baker, Andrea Sottoriva, Gerard Llibre-Palomar
| Nature Verified
Abstract Immune system control is a principal hurdle in cancer evolution. The temporal dynamics of immune evasion remain incompletely characterized, and how immune-mediated selection interrelates with epigenome alteration is unclear. Here we infer the genome- and epigenome-driven evolutionary dynamics of tumor-immune coevolution within primary colorectal cancers (CRCs).
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