German Cuevas-Rios on Muck Rack

German Cuevas-Rios

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Articles

Decreased sialylation elicits complement‐related microglia response and bipolar cell loss in the mouse retina

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By German Cuevas-Rios, Annemarie Bungartz, Tawfik Abou Assale, Jannis Wissfeld
| Wiley Online Library Verified
1 INTRODUCTION Sialic acids are found at the terminal position of glycosylated proteins and lipids of the cell membrane, a condition referred here as sialylation. Sialylated glycoproteins and glycolipids exert anti-inflammatory and antioxidative effects via binding to sialic-acid-binding immunoglobulin-like lectins (Siglec) receptors and regulatory complement factors (Klaus et al., 2021; Lünemann et al., 2021).
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