Geroge Kuo on Muck Rack

Geroge Kuo

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Articles

iCLAP: an innovative method for integrable co-detection of low-abundance antigens with high-plex immunostaining - Nature Communications

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By Fan Wu, Shuyuan Zheng, Yani Chen, Peijia Ye, Moo Joong Kim, Seojin Lee, Geroge Kuo, Shriya Pillan, Ruihan Yuan, Bofei Yu, Qingfeng Zhu, Sarah Shin, Courtney Cannon, Gabriele Pierre, Kanako Iwasaki, Cristina Aguayo-Mazzucato, Nicolas Musi, George A. Kuchel, Birgit Schilling, Laura Wood, Won Jin Ho, Robert A. Anders, Denis Wirtz, Pei-Hsun Wu
| Nature Verified
Abstract Multiplexed protein imaging enables spatial analysis of complex tissues, but detecting proteins expressed at low levels remains challenging, particularly in widely available formalin-fixed, paraffin-embedded (FFPE) specimens. Many biologically important regulators—including senescence markers, transcription factors, and secreted proteins—are therefore difficult to study in situ using existing high-plex methods.
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