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Giarita Ferraro on Muck Rack

Giarita Ferraro

As seen in: Nature, Wiley Online Library, MDPI, ACS Publications, Royal Society of Chemistry, Chemistry World
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Articles

First crystal structure of an adduct formed upon reaction of a vanadium compound with human serum transferrin - Communications Chemistry

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By Rosanna Lucignano, Maddalena Paolillo, Virginia Cuomo, Marco Chino, Giarita Ferraro, Delia Picone, Eugenio Garribba, Anne-Sophie Banneville, Irina Cornaciu-Hoffmann, Andrea Pica
| Nature Verified
Abstract The interaction of vanadium compounds of pharmaceutical interest with metal-transport proteins like human serum transferrin (hTF) is poorly understood. Direct structural evidence identifying vanadium binding sites on hTF is still lacking.
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Speciation and structural transformation of a VV-malate complex in the absence and in the presence of a protein: from a dinuclear species to decavanadate

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By Eugenio Garribba, Antonello Merlino, Maddalena Paolillo, Giarita Ferraro
| Royal Society of Chemistry Verified
Speciation and structural transformation of a VV-malate complex in the absence and in the presence of a protein: from a dinuclear species to decavanadate A strategy for the development of new vanadium-based drugs is the preparation of complexes that target proteins and bear molecules involved in the cellular metabolism as ligands, like αhydroxycarboxylic acids.
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Cytotoxicity and Binding to DNA, Lysozyme, Ribonuclease A, and Human Serum Albumin of the Diiodido Analog of Picoplatin

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By Giarita Ferraro, Jitka Pracharova, Giovanni Gotte, Lara Massai
| ACS Publications
Introduction Click to copy section linkSection link copied! Cisplatin (Figure 1), carboplatin, and oxaliplatin are used to treat many solid tumors, either alone or in combination with other anticancer agents. (1−3) According to the United States’ National Cancer Institute (NCI) database, 10–20% of all cancer patients are treated with these Pt-based drugs (https://www.cancer.gov/research/progress/discovery/cisplatin).
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