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Microglia remodel synapses by presynaptic trogocytosis and spine head filopodia induction
C57BL/6J mice were obtained from local EMBL colonies. Thy1::EGFP; Cx3cr1::CreER; RC::LSL-tdTomato triple transgenic mice were obtained by crossing Thy1::EGFP-M21 (Jackson Laboratory stock 007788) with Cx3cr1::creER-YFP16 (Jackson Laboratory stock 021160) and Rosa26-CAG::loxP-STOP-loxP-tdTomato-WPRE22 (Jackson Laboratory stock 007905). Mice were used in homozygous state for Thy1::EGFP and in heterozygous state for Cx3cr1::CreER and RC::LSL-tdTomato.
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