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Giulia di Bartolomei on Muck Rack

Giulia di Bartolomei

As seen in: BioRxiv, eLife
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Articles

Dilated cardiomyopathy-associated RNA-binding motif protein 20 regulates long pre-mRNAs in neurons

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By Giulia di Bartolomei, Dietmar Schreiner, Susanne Falkner, Esther EJM Creemers
| eLife
eLife Assessment This study reports that the RNA binding and cardiomyopathy-associated protein RBM20 is expressed in specific populations of neurons in the CNS, where it binds to and regulates the expression of synapse-related RNAs. This is an important finding because it reveals a new mechanism for gene regulation in neurons by an RNA binding protein previously studied in the heart; the authors also provide data to suggest that the mechanism by which RBM20 acts in neurons may be distinct...
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Dilated cardiomyopathy-associated RNA Binding Motif Protein 20 regulates long pre-mRNAs in neurons

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By Peter Scheiffele, Giulia di Bartolomei, Raul Ortiz, Dietmar Schreiner
| BioRxiv
Abstract Precise coordination of molecular programs and neuronal growth govern the formation, maintenance, and adaptation of neuronal circuits. RNA metabolism has emerged as a key regulatory node of neural development and nervous system pathologies. To uncover novel cell-type-specific RNA regulators, we systematically investigated expression of RNA recognition motif-containing proteins in the mouse neocortex.
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Microglia remodel synapses by presynaptic trogocytosis and spine head filopodia induction

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By Neurobiology Unit, Laetitia Weinhard, Urte Neniskyte, Giulia di Bartolomei
| BioRxiv
Microglia remodel synapses by presynaptic trogocytosis and spine head filopodia induction Laetitia Weinhard, Urte Neniskyte, Giulia di Bartolomei, Giulia Bolasco, Pedro Machado, Nicole Schieber, Melanie Exiga, Auguste Vadisiute, Angelo Raggioli, Andreas Schertel, Yannick Schwab, Cornelius T. Gross bioRxiv 190975; doi: https://doi.org/10.1101/190975
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