Giulia Marcassa

1 Introduction Hazelnut and walnut allergy may cause systemic and severe reactions. Their molecular heterogeneity reflects sensitisation to labile cross-reactive allergens and to stable seed storage proteins, including 2S albumins, vicilins (7S globulins), and legumins (11S globulins), which are abundant, heat-stable, digestion-resistant, and associated with clinically relevant nut allergy [1-5].

1 Introduction In the last decades, the approach to asthma management has undergone a paradigm shift, evolving from the concept of asthma control to that of asthma remission. Traditionally, asthma management focused on symptom control through a stepwise increase in therapy aimed at minimizing exacerbations and maintaining daily functioning. However, with the advent of biologics, the goal of asthma treatment has expanded to include the potential for achieving remission [1].