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G.K.A Hochberg on Muck Rack

G.K.A Hochberg

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Structural variation of types IV-A1- and IV-A3-mediated CRISPR interference - Nature Communications

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By N. A. Klein, F. Paul BENZ, H. Becker, A. Mikšys, A. Skorupskaitė, G. Žvejytė, N. Steube, G.K.A Hochberg, L. Randau, R. Pinilla-Redondo, L. Malinauskaitė
| Nature Verified
Abstract CRISPR-Cas mediated DNA-interference typically relies on sequence-specific binding and nucleolytic degradation of foreign genetic material. Type IV-A CRISPR-Cas systems diverge from this general mechanism, using a nuclease-independent interference pathway to suppress gene expression for gene regulation and plasmid competition.
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