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Glory Minabou Ndjite on Muck Rack

Glory Minabou Ndjite

As seen in: BioRxiv, Drug Metabolism and Disposition (ASPET)
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Articles

Gut Microbial Utilization of the Alternative Sweetener, D-Allulose, via AlsE

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By Glory Minabou Ndjite, Angela Jiang, Maggie Grant, Charlotte T Ravel
| BioRxiv
Abstract D-allulose, a rare sugar with emerging potential as a low-calorie sweetener, has garnered attention as an alternative to other commercially available alternative sweeteners, such as sugar alcohols, which often cause severe gastrointestinal discomfort. D-allulose-6-phosphate 3-epimerase (AlsE) is a prokaryotic enzyme that converts D-allulose-6-phosphate into D-fructose-6-phopshate, enabling its use as a carbon source.
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Gut Microbiome-Wide Search for Bacterial Azoreductases Reveals Potentially Uncharacterized Azoreductases Encoded in the Human Gut Microbiome

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By Ashley Weiss, Domenick J. Braccia, Glory Minabou Ndjite, Sophia Levy
| Drug Metabolism and Disposition (ASPET)
Abstract The human gut is home to trillions of microorganisms that are responsible for the modification of many orally administered drugs, leading to a wide range of therapeutic outcomes. Prodrugs bearing an azo bond are designed to treat inflammatory bowel disease and colorectal cancer via microbial azo reduction, allowing for topical application of therapeutic moieties to the diseased tissue in the intestines.
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