Gökmen Altay on Muck Rack

Gökmen Altay

As seen in: The Journal of Immunology
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Articles

RNA-seq preprocessing and sample size considerations for gene network inference

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By Gökmen Altay, Jose Zapardiel-Gonzalo, Bjoern Peters
| biorxiv.org
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Functional Analysis of Immune Signature Genes in Th1* Memory Cells Links ISOC1 and Pyrimidine Metabolism to IFN-γ and IL-17 Production

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By Yulia Kushnareva, Ian Mathews, Alexander Y. Andreyev, Gökmen Altay
| The Journal of Immunology Verified
Yulia Kushnareva, Ian T. Mathews, Alexander Y. Andreyev, Gokmen Altay, Cecilia S. Lindestam Arlehamn, Vijayanand Pandurangan, Roland Nilsson, Mohit Jain, Alessandro Sette, Bjoern Peters and Sonia Sharma J Immunol March 15, 2021, 206 (6) 1181-1193; DOI: https://doi.org/10.4049/jimmunol.2000672 Key Points Functional analysis of Th1* immune signature genes uncovers novel regulators of IFN-γ and IL-17. Loss of ISOC1 impairs CD4+ T cell pyrimidine metabolism, bioenergetics, and cytokine production.
Open in Who Shared Issue with article?

Functional Analysis of Immune Signature Genes in Th1* Memory Cells Links ISOC1 and Pyrimidine Metabolism to IFN-γ and IL-17 Production

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By Ian Mathews, Gökmen Altay, Yulia Kushnareva, Alexander Y. Andreyev
| The Journal of Immunology Verified
Yulia Kushnareva, Ian T. Mathews, Alexander Y. Andreyev, Gokmen Altay, Cecilia S. Lindestam Arlehamn, Vijayanand Pandurangan, Roland Nilsson, Mohit Jain, Alessandro Sette, Bjoern Peters and Sonia Sharma J Immunol February 5, 2021, ji2000672; DOI: https://doi.org/10.4049/jimmunol.2000672 Key Points Functional analysis of Th1* immune signature genes uncovers novel regulators of IFN-γ and IL-17. Loss of ISOC1 impairs CD4+ T cell pyrimidine metabolism, bioenergetics, and cytokine production.
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