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Gongga Lanzi on Muck Rack

Gongga Lanzi

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Thwarting resistance: MgrA inhibition with methylophiopogonanone a unveils a new battlefront against S. aureus - npj Biofilms and Microbiomes

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By Xuerui Guo, Quan Liu, Yicheng Zhao, Gongga Lanzi
| Nature Verified
Abstract Limitations in the clinical treatment of Staphylococcus aureus (S. aureus) infections have arisen due to the advent of antibiotic-resistant strains. Given the immense potential of therapeutic strategies targeting bacterial virulence, the role of MgrA as a pivotal virulence determinant in S. aureus-orchestrating resistance, adherence, and hundreds of virulence targets—becomes indispensable.
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