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URI: https://hdl.handle.net/10115/41055 https://www.hekademos.com/index.php/hekademos/article/view/88 Date: 2024 Abstract Information and Communication Technologies (ICT) are an ideal tool for, through gamification, designing educational projects in training contexts outside the game. Gamification is a learning technique based on game strategies that allows students to learn playfully and actively. This work presents a proposal for educational innovation for learning the history of Madrid.
The regulation of pTyr through PTPs may have promoted the emergence of pTyr-binding domains, i.e. SH2 and PTB domains [22]. The choanozoan SH2 domain characteristically folds into an αβββ(β)α architecture. The β-strands form an antiparallel β-sheet, which separates the α-helices on either site. In the canonical SH2-binding mode, pTyr is coordinated by residues in the conserved Gx[YF]xxR motif of βB and bound between the αA-helix and the β-sheets [25, 102].
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