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Gonzalo Barrientos

As seen in: Wiley Online Library, Austin American-Statesman, BioRxiv, Erbol.com.bo
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Articles

Disruption of ATP Synthase Spatiotemporal Organization, Ca2+ Dynamics, and Contractile Function in Senescent Cardiomyocytes

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By Silke Morris, Nico Marx, Gonzalo Barrientos, Isidora Molina-Riquelme
| Wiley Online Library Verified
1 Introduction Cardiovascular diseases (CVDs) are tightly coupled to aging and are the leading cause of death in the elderly population, accounting for almost 40% of all age-related ailments (Fajemiroye 2018). The process of aging and the onset of age-related CVDs are strongly linked to reduced energy metabolism and decreased mitochondrial function (Abdellatif et al. 2023).
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Multi-scale mitochondrial cristae remodeling links Opa1 downregulation to reduced OXPHOS capacity in aged hearts

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By Isidora Molina-Riquelme, Gonzalo Barrientos, Leonhard Breitsprecher, Wileidy Gómez
| BioRxiv
Abstract Aging is closely associated with cardiovascular diseases, the leading cause of mortality worldwide. Mitochondrial dysfunction is a hallmark of cardiovascular aging because it generates most of the heart's ATP at the cristae, specialized sub-compartments where OXPHOS takes place. In this study, we used multiple-scale electron microscopy approaches to evaluate age-related mitochondrial and cristae ultrastructural alterations in human and mouse hearts.
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Convocan a la Asamblea de la Paceñidad para analizar la reactivación económica, agua y censo

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By Gonzalo Barrientos
| Erbol.com.bo
Título: Convocan a la Asamblea de la Paceñidad para analizar la reactivación económica, agua y censo El director de Gobernabilidad de la Alcaldía de La Paz, Gonzalo Barrientos, en declaraciones a los medios. Foto: GAMLP Para este miércoles fue convocada la Asamblea de la Paceñidad que tiene como agenda la reactivación económica, provisión de agua potable, censo y las agresiones que sufrieron choferes de la Federación de Transporte Chuquiago Marka y comerciantes del mercado Miraflores.
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