Greg Barton

After reading this article, you should be able to: Understand the  of commonly used drugs; Understand how to personalise drug therapy in critical illness according to the physiochemical properties of medicines, patient factors, disease factors and extracorporeal factors; Apply a for dosing strategies in critically ill patients. Critical illness induces pathophysiological changes that cause significant alterations to drug pharmacokinetics and pharmacodynamics (PK-PD)​[1]​.

Fever in a patient with osteomyelitis: the diagnosis could be serotonin syndrome Matthew Gould1, William D Harrison2, Abbey Cahill-Kearns3 and Greg Barton3 1Acute Medicine, St Helens and Knowsley Teaching Hospitals NHS Trust, Prescot, Merseyside, UK 2Orthopaedics, Health Education North West, Liverpool, UK 3Intensive Care, St Helens and Knowsley Teaching Hospitals NHS Trust, Prescot, Merseyside, UK Correspondence to Dr Matthew Gould; matthew.gould{at}doctors.org.uk Abstract Awareness of rare...

Clinical pharmacists reduce medication errors and optimize the use of medication in critically ill patients, although actual staffing level and deployment of UK pharmacists is unknown. The primary aim was to investigate the UK deployment of the clinical pharmacy workforce in critical care and compare this with published standards. Data were received for 279 critical care units in 171 organizations. Clinical pharmacist input was identified for 98.6% of critical care units.