Grigore-Aristide Gafencu on Muck Rack

Grigore-Aristide Gafencu

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Articles

Hematopoietic stem cell heterogeneity and age-associated platelet bias are evolutionarily conserved

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By Philipp Starkl, Merve Aksöz, Alessio Bevilacqua, Grigore-Aristide Gafencu
| Science Magazine Verified
Editor’s summary Hematopoietic stem cells (HSCs) are required for blood cell production throughout life. Murine HSCs can be biased toward the megakaryocyte/platelet lineage, but whether platelet-biased human HSCs exist remains to be determined. Aksöz et al. combined molecular barcoding and single-cell RNA sequencing to track the fate of human HSCs (hHSCs) in vivo.
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