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1 Introduction The maintenance of protein homeostasis, or proteostasis, is essential for cell survival, growth, and division. When misfolded or redundant proteins appear in mammalian cells, they must be eliminated through regulated degradation pathways. Dysregulation of these pathways leads to various diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases [1].
You are already at the latest version Vibration-based sensing systems for deployed industrial fault diagnosis often face incremental fault classes, changing degradation stages, and limited permission to retain historical sensor streams. Static fault classifiers are therefore insufficient for online maintenance settings in which a model must learn new sensor-observed states while preserving previous diagnostic knowledge under a bounded memory budget.
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