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Enhanced anti-hyperuricemic effect of Simiao pill by composite lactic acid bacteria fermentation: ferulic acid and berberine enrichment and URAT1/OAT1/XOD regulation
Abstract Background: Simiao Pill (SP) is a traditional Chinese medicine used to treat hyperuricemia (HUA). Microbial fermentation can enhance the effectiveness of herbal medicines. Objectives: This study aimed to evaluate the effects of composite lactic acid bacteria fermentation on the chemical components of SP and its anti-HUA effect. Methods: This study revealed the contents of fermented Simiao Pill (FSP), and optimized the optimal fermentation conditions.
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