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Guangying Shao on Muck Rack

Guangying Shao

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Urea transporter B–mediated urea uptake–induced protein carbamylation in platelets underlies bleeding in chronic kidney disease

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By Shreya Kashyap, Alan Chramiec, M. Silva, Zhiwei Qiu, Fei Xiong, Zhe Wang, Yingxin Zhao, Shuang Gao, Xin Zhang, Yu Chen, Zhiyan Liu, Ruofei Li, Linyu Cao, Lan Sun, Tianze Sun, Tao Jiang, Min Li, Jie Dong, Baoxue Yang, Yimin Cui, Qian Qian Xiang, Guangying Shao
| Science Magazine Verified
Editor’s summary Abstract Supplementary Materials REFERENCES AND NOTES Information & Authors Metrics & Citations Check Access References Figures Tables Media Share Editor’s summary Patients with advanced chronic kidney disease (CKD) can have platelet dysfunction and consequent bleeding complications with no clear therapeutic options. Qiu et al. found that urea transporter B (UT-B), encoded by the SLC14A1 gene, may regulate bleeding in advanced CKD.
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