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A synthetic heavy chain variable domain antibody library (VHL) provides highly functional antibodies with favorable developability
CONFLICT OF INTEREST STATEMENT All authors declare no competing or financial interests. Supporting Information Filename Description pro70090-sup-0001-Supinfo.docxWord 2007 document , 312.2 KB Data S1. Supporting Information. REFERENCES . Camelid single-domain antibodies: promises and challenges as lifesaving treatments. Int J Mol Sci. 2022; 23:5009. , , , , , , et al. Aggregation-resistant VHs selected by in vitro evolution tend to have disulfide-bonded loops and acidic isoelectric points.
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