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Gulden Akcay

As seen in: MDPI
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Articles

Microenvironments Matter: Advances in Brain-on-Chip

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By Gulden Akcay, Regina Luttge
| ncbi.nlm.nih.gov
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Microenvironments Matter: Advances in Brain-on-Chip

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By Regina Luttge, Gulden Akcay
| MDPI
Abstract : To highlight the particular needs with respect to modeling the unique and complex organization of the human brain structure, we reviewed the state-of-the-art in devising brain models with engineered instructive microenvironments. To acquire a better perspective on the brain’s working mechanisms, we first summarize the importance of regional stiffness gradients in brain tissue, varying per layer and the cellular diversities of the layers.
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