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Guoguang Ying on Muck Rack

Guoguang Ying

As seen in: Color Research & Application, Frontiers
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Articles

Prognostic value of lymphocyte subsets in diffuse large B cell lymphoma

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By Lihua Qiu, Meng Zhao, Xinpei Zhou, Guoguang Ying, Huilai Zhang, Chen Tian, Lijing Xing, Biwen Sun
| Frontiers
ORIGINAL RESEARCH article Volume 15 - 2025 | https://doi.org/10.3389/fonc.2025.1671062 Introduction Diffuse large B-cell lymphoma (DLBCL) is the most common type of adult non-Hodgkin lymphoma (NHL), accounting for 30% to 40% of all NHL cases, which represents a high heterogeneity in histological, immunohistochemical, and molecular characteristics (1–3).
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Glutathione reductase mediates drug resistance in glioblastoma cells by regulating redox homeostasis

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By jing Ren, Zhao Yan, Zhongling Zhu, Shuangshuang Du, Yibo Du, Guoguang Ying
| Color Research & Application Verified
Glutathione (GSH) and GSH-related enzymes constitute the most important defense system that protects cells from free radical, radiotherapy, and chemotherapy attacks. In this study, we aim to explore the potential role and regulatory mechanism of the GSH redox cycle in drug resistance in glioblastoma multiforme (GBM) cells. We found that temozolomide (TMZ)-resistant glioma cells displayed lower levels of endogenous ROS and higher levels of total antioxidant capacity and GSH than sensitive cells.
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