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Articles by Guoping Lu
A practical study on a stepwise simulation intervention guided by video review to improve the quality of cardiopulmonary resuscitation in the pediatric emergency department
Abstract Background: Maintaining high-quality cardiopulmonary resuscitation (CPR) in pediatric emergency departments remains challenging. Evidence supporting integrated quality improvement strategies combining video review and in situ simulation is limited. Objective: To evaluate whether implementation of a video review-guided stepwise quality improvement strategy was associated with improved CPR process quality across three sequential implementation phases.
NSGA-II and Powell Optimized Inverse Design of MAO Coatings Click to copy article link Article link copied!
4.1. Construction of the ComDeep-VAE Framework In machine learning applications with limited data sets, variational autoencoders (VAEs) have been employed to augment training data through statistically consistent synthetic sample generation, thereby improving model generalization.
Genetic and phenotypic characterization of the plasmid-encoded NDM-80 metallo-β-lactamase in Escherichia coli isolated from a pediatric patient
Abstract Introduction: Carbapenem-resistant Enterobacterales (CRE) strains carrying blaNDM variants pose a significant threat to the health of infected patients worldwide. Methods: This study isolated a carbapenem-resistant Escherichia coli (E. coli) strain carrying blaNDM–80 from a patient in an intensive care unit in China.
Ferroptosis mediated by the IDO1/Kyn/AhR pathway triggers acute thymic involution in sepsis - Cell Death & Disease
Abstract Acute thymic involution (ATI) is frequently observed during sepsis, however the underlying mechanisms remain poorly understood. This study demonstrates that ferroptosis plays a crucial role in sepsis-associated ATI. We found that pediatric sepsis patients showed significantly elevated kynurenine (Kyn)/tryptophan (Trp) ratios, indicating increased indoleamine 2,3-dioxygenase 1 (IDO1) activity, along with higher Kyn levels compared to controls.
PHGDH/SYK: a hub integrating anti-fungal immunity and serine metabolism - Cell Death & Differentiation
Abstract Immune cells modify their metabolic pathways in response to fungal infections. Nevertheless, the biochemical underpinnings need to be better understood. This study reports that fungal infection drives a switch from glycolysis to the serine synthesis pathway (SSP) and one-carbon metabolism by inducing the interaction of spleen tyrosine kinase (SYK) and phosphoglycerate dehydrogenase (PHGDH).
Significance of non-DLVO interactions on the co-transport of levofloxacin and titanium dioxide nanoparticles in porous media
Due to the unique properties of nanomaterials, various engineered nanomaterials have been synthesized and applied in different fields. Titanium dioxide nanoparticles (TiO2-NPs), as a very important metal oxide nanoparticle (Wang et al., 2014), have been widely used in commercial applications such as paints, sunscreens, cosmetics, semiconductors and photocatalysts (Cai et al., 2019; Chen et al., 2018). There are three different variants of titanium dioxide: rutile, anatase, and slate.
Bipartite Consensus of Fuzzy Multiagent Systems on Multilayer Coopetition Networks Using Output Measurements and Its Application to Image Communication
Recent years have seen great interest in coordination of multiagent systems due to its practical applications in a variety of areas, such as coordination of unmanned vehicles [1], power sharing in islanded microgrids [2], and formation control of multiple underactuated surface vessels [3].
The nuclear cytokine IL-37a controls lethal cytokine storms primarily via IL-1R8-independent transcriptional upregulation of PPARγ - Cellular & Molecular Immunology
Abstract Cytokine storms are crucial in the development of various inflammatory diseases, including sepsis and autoimmune disorders. The immunosuppressive cytokine INTERLEUKIN (IL)-37 consists of five isoforms (IL-37a-e). We identified IL-37a as a nuclear cytokine for the first time. Compared to IL-37b, IL-37a demonstrated greater efficacy in protecting against Toll-like receptor-induced cytokine hypersecretion and lethal endotoxic shock.
The Effects of Spill Pressure on the Migration and Remediation of Dense Non-Aqueous Phase Liquids in Homogeneous and Heterogeneous Aquifers
3. Results and Discussion 3.1. The Effect of Spill Pressure on DNAPL Migration and Remediation in the Homogeneous Aquifer The simulation results of PCE migration for five scenarios with different spill pressures of contamination sources are shown in . Different scenarios have different results of PCE migration and distribution under different spill pressures. The PCE plumes infiltrate faster in the vertical direction. The PCE releases from the upper layer of the aquifer under spill pressure.
Separations | Free Full-Text | Representative Elementary Volume Estimation and Neural Network-Based Prediction of Change Rates of Dense Non-Aqueous Phase Liquid Saturation and Dense Non-Aqueous Phase Liquid-Water Interfacial Area in Porous Media
Open AccessArticle by Zhou Cheng 1,2,†, Guoping Lu 2,†, Ming Wu 2,3,* and Qusheng Li 4 1 Guangdong Provincial Academy of Environmental Science, Guangzhou 510045, China 2 Guangdong Provincial Research Center for Environment Pollution Control and Remediation Materials, College of Life Science and Technology, Jinan University, Guangzhou 510632, China 3 Guangdong Yixin Ecological Technology Co., Ltd., Guangzhou 510055, China 4 Guangdong Key Laboratory of Environmental Pollution and Health, School...
Combined Effects of Polyamide Microplastics and Hydrochemical Factors on the Transport of Bisphenol A in Groundwater
Abstract : Polyamide (PA) and bisphenol A (BPA) are selected as typical microplastic and endocrine-disrupting chemicals in this study. The adsorption of BPA on the surface of PA and the effect of PA on the transport behavior of BPA in groundwater are systematically investigated using a combination of batch experiments, column experiments and numerical models.
The application of pediatric early warning score (PEWS) in emergency observation room
Objective To explore the value of pediatric early warning scoring system (PEWS) in an emergency observation room in China. Methods The children who had been admitted consecutively to the emergency observation room from Jan, 2019 to Aug, 2020 were selected.
Cobalt-molybdenum synergistic catalysis for the hydrogenolysis of terephthalate-based polyesters
Cobalt–molybdenum synergistic catalysis for the hydrogenolysis of terephthalate-based polyesters† Recycling of polyester waste has become a focus of global attention in recent years.
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