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Guozeng Wang

As seen in: Nature, MDPI
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Articles

CYBRD1 is transcriptionally regulated by RUNX1 and mediates JAK2/STAT3 signaling activation during ovarian cancer progression

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By Yalong Deng, Qiyu Gan, Xia Huang, Liang Zhu, Lina Liu, Guozeng Wang, Linlin Chang, Rui Shi, Sufeng Qiang, Qin Liu, Huimin Lei, Jingxin Cheng, Wenzhi Duan
| Nature Verified
Abstract Metastasis and chemoresistance are the leading causes of death in high-grade serous ovarian carcinoma (HGSOC). Our previous studies revealed that the membrane protein cytochrome b reductase 1 (CYBRD1) is a critical prognostic marker for HGSOC, but its role in HGSOC progression and molecular mechanisms remain unclear. Here, we reveal that CYBRD1 is a druggable factor that drives chemoresistance and tumor progression in HGSOC.
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Cancers | Free Full-Text | Prognostic Value and Immune Infiltration of HPV-Related Genes in the Immune Microenvironment of Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma

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By Rui Shi, Qiyu Gan, Linlin Chang, Guozeng Wang
| MDPI
Open AccessArticle by Qiyu Gan 1,†, Luning Mao 2,†, Rui Shi 1, Linlin Chang 1, Guozeng Wang 1, Jingxin Cheng 1,* and Rui Chen 3,* 1 Department of Gynecology and Obstetrics, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai 200120, China 2 Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Pathology, Peking University Cancer Hospital & Institute, Beijing 100021, China 3 Department of Gynecology, Shanghai United...
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