Guozhi Yin

Abstract Metabolic dysfunction-associated steatotic liver disease (MASLD) remains a major global health burden with limited therapeutic options. Heat shock factor 2 binding protein (HSF2BP), originally characterized as a germ cell-specific regulator of meiosis, is significantly upregulated in both MASLD patient livers and high-fat diet (HFD)-fed mice. Here, we identify HSF2BP as a key metabolic regulator in hepatocytes that alleviates hepatic lipid accumulation by enhancing mitochondrial function.

Back to Journals » Clinical Epidemiology » Volume 17 Authors Yang X , Li Q , He Y, Yin G, Li M, Zhu W, Fan X , Gong Y, Wang Y, Qiang W , Wang Y, Willems van Dijk K, Rensen PCN, Guo H, Shi B , Wang Y Received 23 April 2025 Accepted for publication 25 September 2025 Published 14 October 2025 Volume 2025:17 Pages 823—835 DOI https://doi.org/10.2147/CLEP.S536091 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Professor...

Retraction Note: BCORL1 is an independent prognostic marker and contributes to cell migration and invasion in human hepatocellular carcinoma BMC Cancer volume 23, Article number: 542 (2023) Cite this article The Original Article was published on 15 February 2016 Retraction Note: BMC Cancer 16, 103 (2016) The Editors have retracted this article because of irregularities in Figure 3, specifically: In Figure 3B the panel Migration vs. Scrambled siRNA overlaps with the panel Invasion vs.