Gürol M. Süel on Muck Rack

Gürol M. Süel

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Articles

Ribosomal allostery as a potential regulator of bacterial dormancy

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By Eun Chae Moon, S. Banu Ozkan, Danis Yangaliev, Gürol M. Süel
| Nature Verified
Abstract Ribosomes are central to protein synthesis but also serve as dynamic hubs that integrate cellular stress responses. Here, we investigate how ribosomal protein L11 regulates ribosome conformational dynamics and long-distance coupling. Long-timescale molecular dynamics simulations of wild-type and L11-deleted (ΔL11) ribosomes reveal that L11 functions as a global allosteric regulator coordinating communication between the ribosomal stalk and the peptidyl transferase center.
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