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Gustavo Morrone

As seen in: Biomed Central (BMC)
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Articles

Mutations in PSEN1 predispose inflammation in an astrocyte model of familial Alzheimer’s disease through disrupted regulated intramembrane proteolysis | Molecular Neurodegeneration | Full Text

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By Movement Neuroscience, Gustavo Morrone
| Biomed Central (BMC)
Patient-derived iPSCs were established under Joint Research Ethics Committee approval (09/H0716/64). All iPSC lines used in this study have been characterised and described previously, with the exception of the isogenic corrected R278 line following the protocol described previously [32] using the CRISPR/Cas9 technology [33]. Briefly, iPSC cultured in mTeSR-Plus medium were dissociated as single cells with Accutase (Stem Cell Technologies).
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