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Guy StJ Whitley on Muck Rack

Guy StJ Whitley

As seen in: Journal of Molecular Endocrinology
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Articles

Decidual regulation of trophoblast is altered in pregnancies at risk of pre-eclampsia

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By Alison Wallace, Laura B James-Allan, Guy StJ Whitley, Karin Leslie
| Journal of Molecular Endocrinology Verified
Successful implantation and placentation are dependent on the interaction between decidual stromal cells (DSC) and extravillous trophoblast (EVT) cells. The extent of trophoblast invasion relies on communication between the placenta and maternal decidua. The cyclical process of decidualisation induces a transformation of endometrial fibroblasts to secretory DSC; these secreted products have many functions including the control of trophoblast invasion.
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