Skip to main content
GWA-PA Consortium on Muck Rack

GWA-PA Consortium

As seen in: Nature
Is this you? As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work. Claim your profile

Get in touch with GWA-PA

Contact GWA-PA, search articles and posts on X, monitor coverage, and track replies from one place.

Learn more about Muck Rack

Actions

Share this page

Is this you?

As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
Claim your profile

Articles

GWAS of random glucose in 476,326 individuals provide insights into diabetes pathophysiology, complications and treatment stratification - Nature Genetics

|
By Alessia Faggian, Alessia David, Reedik Mägi, Emma Ahlqvist, Gudmar Thorleifsson, Robert Scott, Aaron Isaacs, Christian Gieger, Rona J. Strawbridge, Anuj Goel, Anne Jackson, Heather M. Stringham, Eric Farber-Eger, Valgerdur Steinthorsdottir, André G. Uitterlinden, Patricia B Munroe, Morris Brown, Barbara Thorand, Tom Wilsgaard, Karen L. Mohlke, Zhe Wang, GWA-PA Consortium, Wolfgang Koenig, Inês Barroso, Jaakko Tuomilehto, Michael Boehnke, Mark Caulfield, Nicholas J Wareham, Claudia Langenberg, Grant W. Montgomery, Ioanna Tzoulaki, Paul Elliott, Kari Stefansson, Evan L. Brittain, Mark McCarthy, Philippe Froguel, Leif Groop, Josée Dupuis, James B. Meigs, Giuseppe Deganutti, Yurii S. Aulchenko, Ben Jones, Inga Prokopenko
| Nature Verified
Abstract Conventional measurements of fasting and postprandial blood glucose levels investigated in genome-wide association studies (GWAS) cannot capture the effects of DNA variability on ‘around the clock’ glucoregulatory processes. Here we show that GWAS meta-analysis of glucose measurements under nonstandardized conditions (random glucose (RG)) in 476,326 individuals of diverse ancestries and without diabetes enables locus discovery and innovative pathophysiological observations.
Open in Who Shared Issue with article?
See all 1 articles