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Articles

Paeonol from Paeonia lactiflora attenuates calcification of aortic valvular interstitial cell by inhibiting activation of redox-sensitive NFκB/AKT/ERK1/2 pathway.

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By Ko JY, Gwak YH, Sim HH
| greenmedinfo.com
Abstract <p>Calcific aortic valve disease (CAVD) is a life-threatening cardiovascular condition without effective pharmacological treatments. Paeonol, a bioactive compound from the roots of Paeonia lactiflora, is known for its anti-inflammatory, antioxidant, and anti-atherosclerotic properties. While it has shown benefits in treating several cardiovascular conditions, its role in CAVD remains unexplored, requiring further investigation.
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