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H. Bard on Muck Rack

H. Bard

As seen in: Canadian Journal of Cardiology
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Articles

ALLOGENIC RECELLULARIZATION OF BOVINE PERICARDIUM USING HUMAN MESENCHYMAL STEM CELLS REDUCES IMMUNE MEDIATED REJECTION AGAINST XENOGENIC TISSUES

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By J. E. Kang, H. Bard, A. Alam, S. J. Bozso, D. H. Freed, J. Nagendran, M. Hassanabad, N. Vankka, G. Rayat
| Canadian Journal of Cardiology Verified
Bioprosthetic heart valves (BHV) undergo time and age-dependent structural valve deterioration (SVD). Prior research has shown that SVD is mediated by an immune-mediated rejection process. Tissue-engineered heart valves (TEHV) have been created to attenuate this immune rejection by removing xenogenic cells from the BHV followed by recellularizing the scaffold with mesenchymal stem cells (MSC).
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