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Statistical Analysis Plan for the INTEnsive ambulance-delivered blood pressure Reduction in hyper-ACute stroke Trial (INTERACT4).
Introduction: Recruitment is complete in the fourth INTEnsive ambulance-delivered blood pressure Reduction in hyper-ACute stroke Trial (INTERACT4) is a multicenter, prospective, randomized, open-label, blinded endpoint assessed trial of pre-hospital blood pressure (BP) lowering initiated in the ambulance for patients with a suspected acute stroke and elevated BP in China.
Update on the INTEnsive ambulance-delivered blood pressure Reduction in hyper-ACute stroke Trial (INTERACT4): progress and baseline features in 2053 participants | Trials | Full Text
Controversy persists over the balance of potential benefits and risks of intensive blood pressure (BP) lowering treatment in acute stroke [1, 2], but especially in the pre-hospital ambulance setting considering recent randomized evidence.
The predictive validity of a Brain Care Score for dementia and stroke: data from the UK Biobank cohort
Introduction The global brain health crisis is now recognized as among the greatest threats to human well-being (1–4). Currently, in the United States of America (USA), one out of seven people suffers from dementia (5), which is expected to be tripled by 2050 (6). A stroke-related death occurs every 4 min in the USA, with 13 million annual deaths attributable to new stroke cases by 2050 (7, 8).
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