H. Lee Barnes
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Our Week in Reviews: 11/8/25
Unabridged: The Thrill of (and Threat to) the Modern Dictionary by Stefan Fatsis (Atlantic Monthly Press). Reviewed by Randy Cepuch. “His lifelong love of dictionaries led him to do a story for Slate about how rapidly things were changing in lexicography (noun: ‘the process of writing, editing, or compiling a dictionary’).
A PROSPECTIVE STUDY USING WHOLE EXOME SEQUENCING (WES) IN A CANADIAN POPULATION WITH HYPERTROPHIC CARDIOMYOPATHY
An increasing number of genes are being identified as causes of hypertrophic cardiomyopathy (HCM). A human genome consists of about 20,000 genes - whole exome sequencing (WES) is an analysis of the coding region of these genes. The diagnostic evaluation of HCM in Canadian centres exclusively consists of a ‘gene panel’ which is an arbitrary list of a small number of genes (∼0.1%) compared to WES. There are no prospective studies on Canadians on the utility of WES for genetic cardiomyopathy.
Villa star Watkins shines as they beat Leicester
Leicester's first game since Brendan Rodgers' departure on Sunday ended in a 2-1 defeat against Aston Villa at the King Power Stadium. The Foxes, led by caretaker bosses Mike Stowell and Adam Sadler after Rodgers' exit by "mutual agreement", have now gone seven league games without a win and sit second bottom of the table.
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