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Ha-Neui Kim

As seen in: Nature, Wiley Online Library, BioRxiv
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Articles

Oestradiol and osteoclast differentiation: Effects on p53 and mitochondrial metabolism

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By Adriana Marques-Carvalho, Beatriz Silva, Francisco Pereira, Ha-Neui Kim
| Wiley Online Library Verified
DATA AVAILABILITY STATEMENT The authors confirm that the data supporting the findings of this study are available within the article and its supplementary materials. Raw data were generated at the University of Coimbra and the University of Arkansas for Medical Sciences. Derived data supporting the findings of this study are available from the corresponding author (VS) on request.
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Peptidylarginine deiminase 2 plays a key role in osteogenesis by enhancing RUNX2 stability through citrullination - Cell Death & Disease

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By Ha-Neui Kim
| Nature Verified
Abstract Peptidylarginine deiminase (PADI) 2 catalyzes the post-translational conversion of peptidyl-arginine to peptidyl-citrulline in a process called citrullination. However, the precise functions of PADI2 in bone formation and homeostasis remain unknown. In this study, our objective was to elucidate the function and regulatory mechanisms of PADI2 in bone formation employing global and osteoblast-specific Padi2 knockout mice.
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The NAD salvage pathway in mesenchymal cells is indispensable for skeletal development in mice - Nature Communications

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By Aaron Warren, Ryan Porter, Ha-Neui Kim, Intawat Nookaew, Roy Morello
| Nature Verified
Abstract NAD is an essential co-factor for cellular energy metabolism and multiple other processes. Systemic NAD+ deficiency has been implicated in skeletal deformities during development in both humans and mice. NAD levels are maintained by multiple synthetic pathways but which ones are important in bone forming cells is unknown.
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