Hadile Kobeissy on Muck Rack

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Articles

Genomic alterations during p53-dependent apoptosis induced by γ-irradiation of Molt-4 leukemia cells

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By Rouba Hage-Sleiman, Hisham Bahmad, Hadile Kobeissy, Zeinab Dakdouk
| PLOS
Molt-4 leukemia cells undergo p53-dependent apoptosis accompanied by accumulation of de novo ceramide after 14 hours of γ-irradiation. In order to identify the potential mediators involved in ceramide accumulation and the cell death response, differentially expressed genes were identified by Affymetrix Microarray Analysis. Molt-4-LXSN cells, expressing wild type p53, and p53-deficient Molt-4-E6 cells were irradiated and harvested at 3 and 8 hours post-irradiation.
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