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Hae Deok Jung on Muck Rack

Hae Deok Jung

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Articles

Machine learning-guided discovery of natural anti-inflammatory agents targeting NF-κB p65

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By Junkyu Lee, Ayoung Kim, Si-Young Cho, Hyun Kim, Hae Deok Jung, Haechan Sung, Hyoung-June Kim
| Nature Verified
Abstract Natural products with anti-inflammatory properties have broad applications in biotechnology and healthcare, including nutraceuticals and therapeutics. Here, we present a machine learning-guided experimental framework to identify natural anti-inflammatory agents targeting NF-κB p65. A large-scale dataset of 179,771 protein-compound IC50 values was compiled from the Anti-Inflammatory Compounds Database and BindingDB entries associated with inflammation-related pathways.
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