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Haeike Josephy

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Feasibility and safety of GMP-produced stromal vascular fraction for treatment of knee osteoarthritis: a phase I, first-in-human clinical study with two separated injections

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By Bernard Depypere, Nele Arnout, Luc Vanden Bossche, Sofie Herregods, Ramon Llull, Jan Victor, Phillip N Blondeel, Bart Vandekerckhove, Gaël Martens, Haeike Josephy, Sofie Leyman
| Nature Verified
Abstract The stromal vascular fraction (SVF), derived from adipose tissue, holds promise for the treatment of osteoarthritis (OA) owing to its regenerative and immunomodulatory properties. Clinical implementation, however, is constrained by logistical and regulatory challenges.
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