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Hagop J. Chinchinian on Muck Rack

Hagop J. Chinchinian

As seen in: BioRxiv
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Articles

Multiomics characterization of cell type repertoires for urine liquid biopsies

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By Sevahn Vorperian, Brian DeFelice, Brian Defelice, Joseph A. Buonomo, Hagop J. Chinchinian
| BioRxiv
Abstract Urine is assayed alongside blood in medicine, yet current clinical diagnostic tests utilize only a small fraction of its total biomolecular repertoire, potentially foregoing high-resolution insights into human health and disease. In this work, we characterized the joint landscapes of transcriptomic and metabolomic signals in human urine. We also compared the urine transcriptome to plasma cell-free RNA, identifying a distinct cell type repertoire and enrichment for metabolic signal.
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