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Hai Xia Xie on Muck Rack

Hai Xia Xie

As seen in: BioRxiv
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Articles

Modulation of Salmonella virulence by a novel SPI-2 injectisome effector that interacts with the dystrophin-associated protein complex.

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By Xiu-Jun Yu, Mei Hong Liu, Hai Xia Xie, Ruhong Hou
| BioRxiv
Abstract The injectisome encoded by Salmonella pathogenicity island 2 (SPI-2) had been thought to translocate 28 effectors. Here, we used a proteomic approach to characterise the secretome of a clinical strain of invasive non-typhoidal Salmonella enterica serovar Enteritidis, that had been mutated to cause hyper-secretion of the SPI-2 injectisome effectors. Along with many known effectors, we discovered the novel SseM protein.
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