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1 Introduction Ischemic stroke is caused by the occlusion of cerebral arteries, accounting for approximately 80% of all stroke cases (Y. Wang et al. 2025; Iadecola and Anrather 2011). Rapid restoration of cerebral perfusion is currently the first-line therapeutic strategy for ischemic stroke, represented by intravenous thrombolysis (Bangad et al. 2023).
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