Hailey I Edelstein on Muck Rack

Hailey I Edelstein

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Articles

Enhancing extracellular vesicle cargo loading and functional delivery by engineering protein-lipid interactions - Nature Communications

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By Justin A. Peruzzi, Taylor F Gunnels, Hailey I Edelstein, Peilong Lu, David Baker, Joshua Leonard
| Nature Verified
Abstract Naturally generated lipid nanoparticles termed extracellular vesicles (EVs) hold significant promise as engineerable therapeutic delivery vehicles. However, active loading of protein cargo into EVs in a manner that is useful for delivery remains a challenge.
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Conversion of natural cytokine receptors into orthogonal synthetic biosensors

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By Hailey I Edelstein, William Corcoran, Amparo Cosio, Max L Ezekiel
| biorxiv.org
Abstract Synthetic receptors enable bioengineers to build cell-based therapies that perform therapeutic functions in a targeted or conditional fashion to enhance specificity and efficacy. Although many synthetic receptors exist, it remains challenging to generate new receptors that sense soluble cues and relay that detection through orthogonal mechanisms independent of native pathways.
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Enhancing extracellular vesicle cargo loading and functional delivery by engineering protein-lipid interactions

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By Justin A. Peruzzi, Hailey I Edelstein, Peilong Lu, Taylor F Gunnels
| biorxiv.org
Thank you for your interest in spreading the word about bioRxiv. NOTE: Your email address is requested solely to identify you as the sender of this article. Your Email * Your Name * Send To * Enter multiple addresses on separate lines or separate them with commas. Message Subject (Your Name) has forwarded a page to you from bioRxiv Message Body (Your Name) thought you would like to see this page from the bioRxiv website.
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