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Hainuo Zeng on Muck Rack

Hainuo Zeng

As seen in: Nature
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AFB1 promotes H3N8 replication in chickens by impairing gut colonization of protective segmented filamentous bacteria

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By Mengyue Dong, Yuhang Bai, Ruiheng Liu, Qian Wang, Yuanjia Liu, Qingmei Xie, Xinheng Zhang, Zhenkai Dai, Hainuo Zeng, Runlin Shao, Jiaqian Rao
| Nature Verified
Abstract Aflatoxin B1 (AFB1) is a prevalent mycotoxin in poultry feed, yet its impact on avian influenza virus H3N8 infection remains poorly understood. Here, we show that environmentally relevant concentrations of AFB1 (25–100 μg/kg) significantly enhance H3N8 replication both in chicken cell lines (DF-1 and CEF) and in specific pathogen-free (SPF) chickens.
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