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Haiyin Lai

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MYCN/MNX1 Axis Drives NSCLC Progression by Inducing Macrophage M2 Polarization and CD8+ T Cell Apoptosis via the Wnt/β‐Catenin Pathway

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By Chengzhang Cao, Yuzhen Shi, Haiyin Lai
| Wiley Online Library Verified
Conflicts of Interest The authors declare no conflicts of interest. Supporting Information Filename Description jbt70251-sup-0001-Supplementary_Figure_1.tif345.4 KB Supporting Figure 1. Expression of M2-related factors MRC1 and Ym1. (A-D) PMA-differentiated THP-1 cells were co-cultured with H2170 and A549 NSCLC cells transfected with sh-NC, sh-MNX1, sh-NC+pcDNA, sh-MYCN+pcDNA, or sh-MYCN + MNX1 for 24 h, followed by detection of MRC1 and Ym1 transcripts by quantitative PCR. *P < 0.05.
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