Hajanthy Jeyapragasam on Muck Rack

Hajanthy Jeyapragasam

As seen in: Taylor & Francis Online
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Articles

CYP2C19 and CES1 gene variants affecting clopidogrel metabolism in a South Asian population from Sri Lanka

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By Priyanga Ranasinghe, Hajanthy Jeyapragasam, Nirmala Sirisena, Pulasthi B. Gunarathna
| Taylor & Francis Online
ABSTRACT Aims Clopidogrel exhibits substantial variability in therapeutic response, largely contributed by genetic factors. The pharmacogenomic variants data on clopidogrel metabolism in South Asians have been sparsely studied. This study explores the impact of CYP2C19 and CES1 gene variants on clopidogrel metabolism in Sri Lankans, revealing significant pharmacogenomic insights with broader implications for South Asians.
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Pharmacogenomics in Sri Lanka: a comprehensive systematic review of the research landscape and clinical implications

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By Priyanga Ranasinghe, Nirmala Sirisena, Hajanthy Jeyapragasam, Sandamini Liyanage
| Taylor & Francis Online
Abstract Aim: Pharmacogenomics is emerging in South Asia, including Sri Lanka, with potential to optimize drug therapy and reduce adverse effects. This review evaluates the state of pharmacogenomics research in Sri Lanka, emphasizing population-specific factors to guide future advancements.
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